Chromosomal aberrations and bone marrow toxicity.

Chromosomal aberrations and bone marrow toxicity.

The importance of chromosomal aberrations as a proximate cause of bone marrow toxicity is discussed. Since chemicals that can cause nondisjunction are rare, numerical aberrations (aneuploidy, polyploidy) are not ordinarily important. Many structural aberrations, however, can lead directly to cell death and so are proximate causes of toxicity when they occur. The micronucleus test which utilizes...

Brahmarasayana protects against Ethyl methanesulfonate or Methyl methanesulfonate induced chromosomal aberrations in mouse bone marrow cells

BACKGROUND Ayurveda, the traditional Indian system of medicine has given great emphasis to the promotion of health. Rasayana is one of the eight branches of Ayurveda which refers to rejuvenant therapy. It has been reported that rasayanas have immuno-modulatory, antioxidant and antitumor functions, however, the genotoxic potential and modulation of DNA repair of many rasayanas have not been eval...

The Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Diagnosis of Bone Marrow Metastases

Background: Bone marrow is the site of many malignant disorders and it is one of the common places for solid tumors to metastasize. Examination of the bone marrow aspirate and biopsy is a routine procedure performed for assessment of various conditions such as cytopenias, hematologic neoplasms, nonmalignant disorders and metastatic neoplasms. Methods: The patients were referred to the Hema...

Human Genetics – Chromosomal Aberrations

Nurse and Bone Marrow Transplant

پیوند مغز استخوان باید به مدت طولانی در بیمارستان بستری باشند، که این امر نیز موجب بروز برخی از عوارض روانی مانند: افسردگی، اضطراب، کج خلقی، ترس و ناامیدی در آنان خواهد شد. هرچند که برخورد صحیح کادر مراقبتی درمانی می تواند تا حد زیادی از این عوارض پیشگیری کند. در این مسیر تقویت اعتماد، اعتقاد، امید و تلاش برای سازگاری با مشکل ضرورت دارد. امروزه بسیاری از بیماریهای بدخیم به درمان با پیوند مغز اس...